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Azithromycin Drug Interactions (Cont.)

More Detail About Azithromycin Interactions

 
Pimozide (Orap)
If you are taking azithromycin with pimozide, your body may metabolize the medicines differently than intended and cause an increase in heart toxicity. You should discuss alternate options with your healthcare provider.
 
Warfarin (Coumadin, Jantoven)
If you are taking azithromycin and warfarin, your body may metabolize the medicines differently than intended. Your healthcare provider may choose to monitor your INR and prothrombin time more frequently and adjust accordingly. INR and prothrombin time are tests used to measure how well you blood is clotting.
 
Aluminum or Magnesium Antacids (Maalox, Mylanta, Riopan, Gelusil Rolaids, ALternaGEL, Amphojel, and Others)
If you are taking both azithromycin and antacids made with aluminum or magnesium, less of the azithromycin may be absorbed into your body. Be sure to take the antacids at least two hours before or two hours after taking the azithromycin.
 
Other Aluminum/Magnesium Products
If you are taking azithromycin with products or foods containing aluminum or magnesium, your body may metabolize them differently than intended. When taking azithromycin, it is a good idea to allow at least two hours between the time you take your azithromycin dose and when you take any of the aluminum or magnesium products discussed below. Some common products that contain these substances include supplements, multivitamins with minerals, and laxatives.
 
Digoxin (Digitek, Lanoxicaps, Lanoxin)
When taking azithromycin with digoxin, your body may metabolize the medicines quite differently than intended. You may wish to discuss this with your healthcare provider prior to starting azithromycin.
(Azithromycin Drug Interactions Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;