Azithromycin Drug Interactions

Azithromycin Drug Interactions Explained

The following sections explain in detail how the drugs mentioned above can cause potentially negative interactions when combined with azithromycin.

 

If you are taking azithromycin and warfarin, your body may metabolize warfarin differently than intended, perhaps increasing the risk of bleeding. Your healthcare provider may choose to monitor your INR and prothrombin time more frequently and adjust accordingly. INR and prothrombin time are tests used to measure how well you blood is clotting.

 

If you are taking both azithromycin and antacids made with aluminum or magnesium, azithromycin may not be absorbed into your body as well as usual. Be sure to take the antacids at least two hours before or two hours after taking azithromycin.

 

When taking azithromycin with digoxin, your body may metabolize digoxin differently than intended, increasing the risk of digoxin toxicity. You may wish to discuss this with your healthcare provider prior to starting azithromycin.

 

If you are taking azithromycin and tacrolimus together, your body may metabolize tacrolimus differently than intended and significantly increase the levels of the drug in your system. Your healthcare provider may choose to monitor your progress and adjust your dose accordingly.

 

If you are taking both azithromycin and cyclosporine, your body may metabolize cyclosporine differently than intended and significantly increase the drug level in your system. Your healthcare provider may choose to monitor your progress and adjust your dose accordingly.