Azithromycin Drug Interactions

Cyclosporine (Gengraf, Neoral, Sandimmune, Restasis)
If you are taking both azithromycin and cyclosporine, your body may metabolize cyclosporine differently than intended and significantly increase the drug level in your system. Your healthcare provider may choose to monitor your progress and adjust your dose accordingly.
 
Phenytoin (Dilantin, Phenytek)
If you are taking azithromycin with phenytoin, your body may metabolize phenytoin than intended and significantly increase the level of the drug in your system. Your healthcare provider may choose to monitor your progress and adjust your dose accordingly. This interaction has not been demonstrated with azithromycin specifically but has been reported with other similar antibiotics.
 
Triazolam (Halcion)
If you are taking both azithromycin and triazolam, your body may metabolize triazolam differently than intended and significantly increase the drug level in your system. Your healthcare provider may choose to monitor your progress and adjust your dose accordingly. This interaction has not been demonstrated with azithromycin specifically but has been reported with other similar antibiotics.
 
Ergot Alkaloids
Taking ergot medications with antibiotics similar to azithromycin may increase the risk of ergot toxicity. Your healthcare provider may choose to monitor your progress and adjust your dose accordingly. This interaction has not been demonstrated with azithromycin specifically but has been reported with other similar antibiotics.
 
Theophylline (Elixophyllin, Theo-24, Uniphyl, TheoCap, Theochron)
If you are taking azithromycin with theophylline, your body may metabolize theophylline differently than intended and perhaps increase the levels of these drugs in your system. Your healthcare provider may choose to monitor your progress and adjust your dose accordingly.
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Azithromycin Information

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