You should talk with your healthcare provider prior to using this medication if you have:
- Kidney disease, such as kidney failure (renal failure)
- Liver disease, such as hepatitis, cirrhosis, or liver failure
- Had a bone marrow transplant or will be undergoing a bone marrow transplant
- Had or will be having radiation treatment
- Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Azactam and Pregnancy)
- Breastfeeding (see Azactam and Breastfeeding).
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Aztreonam Injection to learn more, including information on who should not use the drug.)
Aztreonam injection is an antibiotic medicine that works by killing bacteria. It does this by preventing the bacteria from making their cell walls. Because bacteria need their cell walls to survive, this causes the bacteria to die.
Some general considerations for when and how to use aztreonam injection include the following:
- This medication is given as an injection into a vein (an intravenous, or IV, injection) or a muscle (an intramuscular, or IM, injection). It is usually given every 6 to 12 hours.
- Intravenous doses may be given directly into a vein over 3 to 5 minutes, or as a slow injection (an IV infusion) over a 20- to 60-minute period. IM injections are given into a large muscle, such as the buttocks or thigh.
- IV administration is recommended for serious infections and in the treatment of children.
- In general, aztreonam injection treatment will continue for at least 48 hours after your infection has cleared to make sure the infection is entirely gone.
- For the medication to work properly, it must be used as prescribed. You should finish the entire course of this medication, even if you feel better. Skipping doses or stopping it too early could cause your infection to return or lead to the development of antibiotic-resistant bacteria.