How Does Bactroban Work?Bactroban works by interfering with bacterial protein synthesis. This means that it stops bacteria from making important proteins. More specifically, it works by binding to an important bacterial enzyme known as isoleucyl transfer-RNA synthetase. This medication works against a wide range of bacteria, including (most notably) MRSA.
Can Children Use Bactroban?Bactroban skin ointment is approved for children as young as two months old. The skin cream is approved for use in children as young as three months of age. The nasal ointment is approved only for individuals age 12 and older, as it has not been adequately studied in younger children.
Off-Label Bactroban UsesOn occasion, your healthcare provider may recommend this product for something other than the uses discussed in this article (this would be known as an "off-label" use). Bactroban nasal ointment is sometimes used off-label to rid the nose of MRSA bacteria in individuals planning an elective surgery in order to help prevent surgical infections, since the MRSA in the nose could lead to an infection elsewhere in the body, such as the surgical site.