Cefixime Side Effects

Clinical studies have shown that nausea, diarrhea, and heartburn are among the most common side effects of cefixime. Although reactions to this antibiotic tend to be minor and easy to treat, serious reactions can also occur. Contact your healthcare provider right away if you develop problems like watery or bloody diarrhea, seizures, or unusual muscle movements.

An Introduction to Side Effects of Cefixime

Just like any medicine, cefixime (Suprax®) can cause side effects. However, not everyone who takes the drug will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with this drug. Your healthcare provider can discuss a more complete list with you.)

Cefixime Side Effects to Report

Some side effects of cefixime are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Signs of an overdose, such as:
    • Seizures
    • Coma
    • Unusual muscle movements or hyperactivity
  • Watery or bloody diarrhea, which may start while taking the drug or even quite a while after treatment ends
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Itching
    • Hives
    • Redness of the face
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.

Common Side Effects

Cefixime has been studied extensively in clinical trials. In these studies, the possible side effects were carefully documented.
Based on these studies, the most common cefixime side effects included:
  • Diarrhea -- in up to 16 percent of people
  • Nausea -- up to 7 percent
  • Loose or frequent stools -- up to 6 percent
  • Passing gas -- up to 4 percent
  • Abdominal (stomach) pain -- up to 3 percent
  • Indigestion or heartburn -- up to 3 percent.
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Cefixime Antibiotic Information

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