Drug Interactions With Cefotetan

Birth Control Pills
Despite the long-standing belief that antibiotics interact with birth control pills, several studies have shown that most antibiotics do not increase the risk of pregnancy in women taking birth control pills. Nevertheless, there have been reports of birth control pill failure in women who have taken antibiotics.
 
Ask your healthcare provider about whether you need to use a backup method of birth control while using cefotetan (see Antibiotics and Birth Control Pills for more information). If it is very important to you to avoid pregnancy, you might consider using a backup method just to be safe.
 
Oral Typhoid Vaccine
Like other antibiotics, cefotetan may decrease the effectiveness of the oral typhoid vaccine. If you have received cefotetan recently, or are currently using this medication, your oral typhoid vaccine may need to be postponed for at least a day after receiving cefotetan.
 
Probenecid
Probenecid can decrease the body's ability to remove cefotetan from the blood, potentially leading to high cefotetan blood levels. Talk with your healthcare provider before using these medications together. In general, people taking probenecid should receive no more than 6 grams of cefotetan per day.
 
Warfarin
There have been reports that cephalosporin antibiotics, including cefotetan, can increase the anticoagulant effects of warfarin. If you are using warfarin, close monitoring will be necessary during cefotetan treatment and for a while after treatment ends. Your warfarin dosage may need to be temporarily adjusted.
 

Final Thoughts

It is possible that not all cefotetan drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific interactions that may apply to you.
 

Cefotetan Drug Information

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