Precautions and Warnings With Ceftibuten

Tell your healthcare provider if you have ever had problems with penicillin or other cephalosporin antibiotics before using ceftibuten. Some people who are allergic to these types of antibiotics may also be allergic to ceftibuten. Other warnings to be aware of before taking this drug include precautions for potential drug interactions and possible risks for women who are pregnant or breastfeeding.

 

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking ceftibuten (Cedax®) if you have:
 
  • Kidney disease, such as kidney failure (renal failure)
  • An allergy to cephalosporin or penicillin antibiotics
  • Any other allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
 
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 

Specific Ceftibuten Precautions and Warnings

Some warnings and precautions to be aware of prior to taking this medication include the following:
 
  • Ceftibuten contains an antibiotic that belongs to the cephalosporin group of antibiotics, which are related to penicillin medications. Some people who are allergic to penicillin will also be allergic to ceftibuten. An allergic reaction can be quite dangerous. Let your healthcare provider know immediately if you notice any signs of an allergic reaction, such as:
    • A rash
    • Itching
    • Hives
    • Wheezing
    • Swelling of the mouth or lips
    • Difficulty breathing.
 
  • Make sure your healthcare provider knows if you have kidney disease, as the kidneys remove ceftibuten from the body. If your kidneys are not functioning well, you will need a lower and/or less frequent dosage.
 
  • Let your healthcare provider know if you experience bloody or watery diarrhea. While diarrhea is a common side effect of ceftibuten, bloody or watery diarrhea may be a sign of a serious reaction that can occur when certain bacteria (Clostridium difficile) overgrow in the colon. This severe reaction can occur long after you stop using the drug and can be life-threatening.
 
  • Antibiotics can sometimes cause yeast infections, as they can get rid of "good" bacteria that help protect against yeast infections. Let your healthcare provider know if you develop a vaginal yeast infection or thrush (a yeast infection of the mouth) during treatment.
 
  • Ceftibuten should not be used to treat viruses, such as the common cold or the flu. This drug is completely ineffective for treating viruses, and such use can lead to bacterial resistance.
     
  • This medication can impair the body's ability to form blood clots, especially in people who are already at risk for bleeding, including those with liver or kidney disease or people taking "blood thinners" (anticoagulants).
   
  • Ceftibuten is a pregnancy Category B medication. This means that it is probably safe for use during pregnancy, although the full risks are unknown. Talk to your healthcare provider about the risks and benefits of using this drug when pregnant (see Cedax and Pregnancy for more information).
 
  • It is unknown if ceftibuten passes through breast milk. Therefore, if you are breastfeeding or plan to start, talk with your healthcare provider prior to taking this antibiotic (see Cedax and Breastfeeding for more information).
 
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Ceftibuten Drug Information

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