How Does It Work?

Ceftriaxone is part of a class of drugs called cephalosporins. It prevents bacteria's ability to make and maintain their cell wall. Without a cell wall, bacteria are vulnerable and ultimately perish.
Examples of other medicines in this class include Omnicef® (cefdinir) and Keflex® (cephalexin).


By affecting the cell wall of bacteria, ceftriaxone helps kill bacteria (thus keeping them from infecting the body).

When and How Do I Take Ceftriaxone?

Some general considerations include:
  • The medication is only available as a solution for intramuscular injection or intravenous (IV) administration. It is usually given once or twice a day, depending on your healthcare provider's instructions.
  • The ceftriaxone solution should be clear and contain no visible floating material.
  • It should be injected at the same time each day to maintain an even level of ceftriaxone in your system.
  • For the medication to work properly, it must be administered as prescribed. Your entire course of ceftriaxone will be completed, even if you start feeling better. This will ensure that the infection is completely treated.
  • Outdated ceftriaxone should never be used. Any outdated medication may cause serious problems because the intended effects often change after the expiration date has passed.

Dietary Considerations

There are no diet restrictions with ceftriaxone. Patients should be aware that the medicine does contain a small amount of sodium (83 mg per 1 gram of ceftriaxone).
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