Cipro Drug Interactions

More Detail on Cipro Drug Interactions

The following sections explain in detail the potentially negative interactions that can occur when Cipro is combined with any of the drugs listed above.
 
Aluminum, Calcium, or Magnesium Antacids
Aluminum, calcium, and magnesium can bind to Cipro in the digestive tract, preventing it from being absorbed into the bloodstream. You should take your Cipro dose at least two hours before or six hours after taking any product that contains aluminum, calcium, or magnesium.
 
Caffeine
Cipro may reduce the body's ability to remove caffeine, potentially increasing the effects of caffeine. Therefore, it may be a good idea to limit your caffeine intake while taking Cipro. Keep in mind that many foods and beverages, such as coffee, tea, and chocolate, contain caffeine.
 
Corticosteroids
Corticosteroids seem to increase the risk of tendon problems, including tendon rupture, when combined with Cipro. Older adults appear to have an even higher risk for this reaction. If you take Cipro with a corticosteroid, make sure to watch for any signs of tendon problems, such as tendon or joint pain or tenderness.
 
Didanosine
Some forms of didanosine can bind to Cipro in the digestive tract, preventing it from being absorbed into the bloodstream. You should take your Cipro dose at least two hours before or six hours after taking didanosine. Not all forms of didanosine interact with Cipro, so be sure to ask your pharmacist about this possible interaction with your particular didanosine product.
 
Erlotinib
Cipro may increase the levels of erlotinib in your body, increasing your risk for side effects. If you take these medications together, be watchful for signs of severe erlotinib reactions, including severe diarrhea and skin reactions. Your healthcare provider may need to decrease your erlotinib dose.

Cipro Antibiotic Information

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