Cipro Drug Interactions

Sevelamer
Sevelamer can bind to Cipro in the digestive tract, decreasing the amount that is absorbed into the bloodstream. You should take Cipro at least one hour before or three hours after taking sevelamer.
 
Sucralfate
Sucralfate can bind to Cipro in the digestive tract, decreasing the amount that is absorbed into the bloodstream. You should take your Cipro dose at least four hours before or six hours after taking sucralfate.
 
Sulfonylureas
There have been reports of changes in blood sugar levels (both low and high) in people taking sulfonylureas with Cipro. Low blood sugar levels (hypoglycemia) may be more likely within the first couple of days of Cipro treatment, while high blood sugar levels (hyperglycemia) may be more likely to occur after several days. If you take a sulfonylurea, your healthcare provider may recommend that you check your blood sugar levels more often while taking Cipro.
 
Theophylline
Cipro may increase the level of theophylline in your blood, potentially increasing your risk for serious side effects, such as seizures. If you take these medications together, your healthcare provider may want to monitor the level of theophylline in your blood.
 
Tizanidine
Cipro may increase the amount of tizanidine in your blood, increasing your risk for side effects, such as sedation or low blood pressure (hypotension). The manufacturer of Cipro recommends that these medications should not be taken together. If your healthcare provider recommends you take tizanidine with Cipro, you may need to be watchful for tizanidine side effects.
 
Typhoid Vaccine
Antibiotics, including Cipro, may decrease the effectiveness of the typhoid vaccine. This interaction only occurs with the oral typhoid vaccine. It is generally recommended that the oral typhoid vaccine be postponed for at least a day after finishing Cipro.

Cipro Antibiotic Information

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