How Does Cipro Work?Cipro works by killing certain bacteria that cause infections. It does this by interfering with two bacterial enzymes called topoisomerase IV and DNA gyrase. These enzymes are needed by the bacteria to copy and repair DNA, important steps required for the bacteria to multiply.
Can Children Use It?Cipro is approved to prevent an infection after anthrax exposure in children. It is also approved to treat serious urinary tract and kidney infections in children. However, Cipro is often not the first choice for treating infections in children because it may cause bone, joint, or tendon problems in this age group (see Cipro and Joint Pain).
Can Older Adults Use Cipro?This drug is often used to treat infections in older adults. However, older adults may have an increased risk for certain Cipro side effects, such as QT prolongation (a problem with the heart rhythm) and tendon problems (see Cipro Tendon Rupture). Studies have shown that tendon problems, including tendon rupture, are more likely to occur in older adults who are also taking corticosteroid medications (such as prednisone).
In addition, kidney function often declines with age. Because the kidneys remove Cipro from the body, older adults may need a lower Cipro dosage.