How Long Does Cipro Stay in the Body?

When determining how long Cipro stays in the body, it's important to understand the "elimination half-life" of a medication. This is the amount of time it takes for the blood levels of the medication to be reduced by half. Because the elimination half-life of Cipro is about four hours, it means that it will take about 24 hours to completely remove this drug from the body.

An Introduction to Cipro's Effects in the Body

Cipro® (ciprofloxacin) is a prescription medication used to treat a variety of different infections. It is also used to prevent infections, or reduce worsening of infections, after exposure to inhaled anthrax.
 
Some people may wonder how long Cipro stays in the body. In most cases, the body will remove the majority of this medication after approximately one day.
 

Cipro Half-Life

The elimination half-life of a medication is the time it takes for the blood levels of the medication to be reduced by half. The elimination half-life of Cipro in people with normal kidney function is about four hours. This means that every four hours, the level of Cipro in your blood will drop by 50 percent of the previous level.
 
For practical purposes, this means that after one dose, the majority of Cipro would be removed from the body after about 24 hours. However, this medication is usually given twice a day, about every 12 hours, to help maintain an even level of the medication in the bloodstream. This is important to treat an infection.
 
Certain factors, such as kidney function, may affect how long Cipro remains in the body. This is the reason people with kidney disease can sometimes take Cipro less often than twice a day. For example, people with kidney impairment may only take this drug every 18 hours. Those on kidney dialysis may only need to take it once a day.
 
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Written by/reviewed by: Susan Lakey, PharmD, MPH
Last reviewed by: Kristi Monson, PharmD
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