Drug Interactions With Clarithromycin

Pimozide
Combining pimozide with clarithromycin can cause dangerous and possibly life-threatening effects. These medications should never be taken together.
 
QT-Prolonging Medications
Clarithromycin can cause a dangerous change in heart rhythm known as QT prolongation. Combining clarithromycin with other drugs that also have this tendency increases the risk. Check with your healthcare provider before taking any of these medications together.
 
Statins
Clarithromycin may increase the level of statin cholesterol medications in the blood, possible increasing the risk of side effects. Check with your healthcare provider before taking clarithromycin with any statins. Clarithromycin should never be combined with lovastatin or simvastatin.
 
Theophylline
Clarithromycin may increase the level of theophylline in your blood. Your healthcare provider may want to monitor the level of theophylline in your blood if you are taking both of these medications.
 
Warfarin
There have been reports that combining clarithromycin with warfarin may increase the risk of bleeding. If you take these medications together, your healthcare provider may need to monitor you more closely.
 

Final Thoughts on Drug Interactions With Clarithromycin

Not all interactions were discussed in this article. Compared to many other medications, clarithromycin has a high likelihood for drug interactions. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions with clarithromycin that may apply to you.
 
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