Drug Interactions With Clarithromycin

If you are taking certain medications with clarithromycin, drug interactions may occur. Some of these interactions may alter the amounts of the medications in your blood, possibly increasing your risk of side effects or other problems. A few of the drugs that can potentially interact with clarithromycin include benzodiazepines, erectile dysfunction medications, and statins.

Are There Drug Interactions With Clarithromycin?

Clarithromycin (Biaxin®) can potentially interact with many medications, too many to list here. Some (but not all) of the medicines that may lead to drug interactions include:
    • Bromocriptine (Parlodel®)
    • Dihydroergotamine (Migranal®)
    • Ergonovine
    • Ergotamine (Bellamine S, Cafergot®, Ergomar®)
    • Methylergonovine (Methergine®)
    • Pergolide (Permax®)
  • HIV/AIDS medications
  • Phosphodiesterase type 5 inhibitors (PDE5 inhibitors), including:


  • Pimozide (Orap®)
  • QT-prolonging medications (drugs that cause an irregular heart rhythm known as QT prolongation)
  • Statin medications, such as:
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Clarithromycin Antibiotic Information

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