You should talk with your healthcare provider prior to taking this medication if you have:
- Kidney disease, such as kidney failure (renal failure)
- Seizures or epilepsy
- Had a heart, liver, or lung transplant
- Rheumatoid arthritis
- Cerebral arteriosclerosis (hardening and thickening of the arteries of the brain)
- Low potassium levels in the blood (hypokalemia)
- Any allergies, including allergies to food, dyes, or preservatives
- Myasthenia gravis.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Levaquin and Pregnancy)
- Breastfeeding (see Levaquin and Breastfeeding).
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Levofloxacin to learn more, including information on who should not take the drug.)
Levofloxacin belongs to a group of medications known as fluoroquinolones, sometimes known just as "quinolones" for short. It works by interfering with two important bacterial enzymes (topoisomerase IV and DNA gyrase). These enzymes are necessary for bacteria to be able to copy and repair DNA (important steps required in order for bacteria to multiply).