Bacteria Home > Aztreonam Injection

Aztreonam injection is a medication used for the treatment of a number of bacterial infections, such as bladder infections, lower respiratory tract infections, and skin infections. The antibiotic, which is available by prescription, is injected into a vein or a muscle every 6 to 12 hours. It works by preventing bacteria from growing and multiplying. Diarrhea, nausea, and vomiting are possible side effects.

What Is Aztreonam Injection?

Aztreonam injection (Azactam®) is a prescription antibiotic approved to treat a wide variety of infections, including infections of the urinary tract, lower respiratory tract, skin, abdomen (stomach), and pelvis. It is also used to manage infections that occur after surgery. It belongs to a class of antibiotics called monobactams.
 
Aztreonam injection is only effective against infections that are caused by bacteria classified as Gram-negative bacteria. Gram-negative bacteria include Escherichia coli (E. coli), Pseudomonas aeruginosa, Klebsiella, and several others.
 
The antibiotic contained in this medicine is also available in an inhaled form -- Aztreonam for inhalation (Cayston®). This form is approved to treat people with cystic fibrosis who have a chronic lung infection due to the bacterium Pseudomonas aeruginosa.
 
(Click What Is Aztreonam Injection Used For? for more information, including possible off-label uses.)
 

Are There Side Effects?

Just like any medicine, aztreonam injection can cause side effects. However, not everyone who uses the drug will experience problems. Most people tolerate it quite well.
 
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
 
Some of the possible side effects of aztreonam injection include but are not limited to:
 
  • Diarrhea
  • Nausea
  • Vomiting
  • Rash
  • Reactions at the site of the injection.
 
(Click Aztreonam Injection Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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