Mefoxin Warnings and Precautions

Before starting treatment with Mefoxin, your healthcare provider will need to know if you have any allergies, kidney disease, or other medical problems. Safety precautions associated with Mefoxin also include warnings for women who are pregnant or nursing. In addition, seek medical attention if you develop any signs of an allergic reaction, as this can lead to dangerous problems.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to receiving Mefoxin® (cefoxitin) if you have:
  • Kidney disease, such as kidney failure (renal failure)
  • An allergy to cephalosporin or penicillin antibiotics
  • Any other allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Mefoxin

Some warnings and precautions to be aware of prior to using this medicine include the following:
  • Mefoxin contains an antibiotic that belongs to the cephalosporin group of antibiotics, which are related to penicillin antibiotics. Some people who are allergic to penicillins will also be allergic to Mefoxin. Because an allergic reaction to Mefoxin can be quite dangerous, let your healthcare provider know immediately if you notice any signs of an allergic reaction, such as:
    • A rash
    • Itching
    • Hives
    • Wheezing
    • Swelling of the mouth or lips
    • Difficulty breathing.
  • Make sure your healthcare provider knows if you have kidney disease, as the kidneys excrete Mefoxin from the body. If your kidneys are not functioning well, you will need a lower and/or less frequent Mefoxin dosage.
  • Let your healthcare provider know if you experience bloody or watery diarrhea. While diarrhea is a common side effect of Mefoxin, bloody or watery diarrhea may be a sign of a serious reaction to Mefoxin that can occur when certain bacteria (Clostridium difficile) overgrow in the colon. This severe reaction can occur long after you stop using Mefoxin and can be life-threatening.
  • Antibiotics, including Mefoxin, can sometimes cause yeast infections, as they can get rid of "good" bacteria that help protect against yeast infections. Let your healthcare provider know if you develop a vaginal yeast infection or thrush (a yeast infection of the mouth) while using Mefoxin.
  • Mefoxin should not be used to treat viruses, such as the common cold or the flu. Mefoxin is completely ineffective for treating viruses, and such use can lead to bacterial resistance to Mefoxin.
  • Mefoxin is a pregnancy Category B medication. This means that it is probably safe for use during pregnancy, although the full risks are currently unknown. Talk to your healthcare provider about the risks and benefits of using this drug during pregnancy (see Mefoxin and Pregnancy for more information).
  • Mefoxin passes through breast milk. Therefore, if you are breastfeeding or plan to start, make sure to talk with your healthcare provider about using Mefoxin (see Mefoxin and Breastfeeding for more information).

Mefoxin Antibiotic Information

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