Drug Interactions With Moxifloxacin

More Information on Interactions With Moxifloxacin

The following sections explain in detail the potentially negative interactions that can occur when moxifloxacin is combined with any of the drugs listed above.
 
Aluminum, Calcium, or Magnesium Antacids
Aluminum, calcium, and magnesium can bind to moxifloxacin in the digestive tract, preventing it from being absorbed into the bloodstream. Be sure to take moxifloxacin at least four hours before or eight hours after a dose of such antacids.
 
Corticosteroids
Corticosteroids seem to increase the risk of tendon rupture due to moxifloxacin. If your healthcare provider recommends taking moxifloxacin with a corticosteroid, be sure to watch for any signs of tendon rupture, such as pain or tenderness.
 
Didanosine
Some forms of didanosine can bind to moxifloxacin in the digestive tract, preventing it from being absorbed into the bloodstream. Be sure to take moxifloxacin at least four hours before or eight hours after a dose of didanosine. Not all forms of didanosine interact with moxifloxacin, so be sure to ask your pharmacist about this possible interaction with your particular didanosine product.
 
NSAIDs
NSAIDs may increase the risk of central nervous system stimulation problems due to moxifloxacin. These problems include:
 
 
Check with your healthcare provider before taking moxifloxacin with an NSAID.
 
Oral Typhoid Vaccine
Antibiotics (including moxifloxacin) may decrease the effectiveness of the oral typhoid vaccine. If you have taken moxifloxacin recently or are currently taking moxifloxacin, your oral typhoid vaccine may need to be postponed for at least a day after taking the antibiotic.

Moxifloxacin Hydrochloride Information

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