An Introduction to Treatment for Myasthenia Gravis
In most people,
myasthenia gravis can be controlled. There are several different therapies that are available to help reduce and improve the symptom of muscle weakness. Most people will have good results with treatment.
According to the Muscular Dystrophy Association, up to 20 percent of people with myasthenia gravis will have complete remission (a period of time without symptoms) without any treatment, and another 20 percent may improve completely without treatment. These spontaneous improvements are more likely to occur during early stages of myasthenia gravis.
Treatment for myasthenia gravis may include:
- Medications
- Thymectomy
- Plasmapheresis or plasma exchange
- High-dose intravenous immune globulin.
Medications
Medications that are used for the treatment of myasthenia gravis include anticholinesterase agents such as neostigmine and pyridostigmine. These medications help to improve neuromuscular transmission and increase muscle strength. Immunosuppressive drugs such as
prednisone, cyclosporine, and
azathioprine may also be used. These medications improve muscle strength by suppressing the production of abnormal antibodies. It is important to note that these medications must be used with careful medical follow-up because they may cause major side effects.