Drug Interactions With Norfloxacin

Clomipramine
Norfloxacin may increase the amount of clomipramine in the bloodstream, potentially increasing your risk for side effects. If you are currently taking clomipramine, talk to your healthcare provider about this interaction before starting treatment with norfloxacin.
 
Corticosteroids
Taking norfloxacin with corticosteroids may increase the risk for tendon problems, including tendon rupture. Older adults appear to be at an even higher risk for these problems. If you take norfloxacin with a corticosteroid, be watchful for any signs of tendon problems, such as tendon or joint pain or tenderness. Report any such problems immediately to your healthcare provider.
 
Cyclobenzaprine
Norfloxacin may increase the amount of cyclobenzaprine in the bloodstream, potentially increasing your risk for side effects. If you are currently taking cyclobenzaprine, talk to your healthcare provider about this interaction before taking norfloxacin.
 
Cyclosporine
Norfloxacin may increase the level of cyclosporine in the bloodstream, potentially causing serious side effects. Check with your healthcare provider before taking these medications together.
 
Didanosine
Some forms of didanosine can bind to norfloxacin in the digestive tract, preventing it from being completely absorbed into the bloodstream. You should take your norfloxacin dose at least two hours before or six hours after didanosine. Not all forms of didanosine react with norfloxacin, so make sure to ask your pharmacist about this possible interaction with your particular didanosine product.
 
Duloxetine
Norfloxacin may increase the amount of duloxetine in the bloodstream, potentially increasing your risk for side effects. If you are currently taking duloxetine, talk to your healthcare provider about this interaction before taking norfloxacin.
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Norfloxacin Drug Information

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