Drug Interactions With Norfloxacin

Flutamide
Norfloxacin may increase the level of flutamide in the bloodstream, potentially increasing your risk for side effects. If you take these medications together, your healthcare provider may choose to monitor you more closely.
 
Fluvoxamine
Norfloxacin may increase the amount of fluvoxamine in the bloodstream, potentially increasing your risk for side effects or low blood pressure. If you take fluvoxamine, talk to your healthcare provider about this interaction before taking norfloxacin.
 
Guanabenz
Norfloxacin may increase the amount of guanabenz in the bloodstream, potentially increasing your risk for side effects. If you take these medications together, your healthcare provider may choose to monitor you more closely.
 
Insulin
There have been reports of changes in blood sugar levels (both low and high) in people taking fluoroquinolones such as norfloxacin. Taking norfloxacin with insulin may increase your risk for these blood sugar problems. If you are currently using insulin, your healthcare provider may recommend that you check your blood sugar levels more often while taking norfloxacin.
 
Iron Supplements
Iron can bind to norfloxacin in the digestive tract, reducing the amount absorbed into the bloodstream. You should take your norfloxacin dose at least two hours before or six hours after any iron supplements to help minimize this interaction.
 
QT-Prolonging Medications
In general, norfloxacin should be used with caution in combination with any other medications that can cause QT prolongation (a certain change in the heart rhythm) due to the risk of a life-threatening arrhythmia. Talk to your healthcare provider about this interaction if you take any QT-prolonging medications.
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Norfloxacin Drug Information

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