Drug Interactions With Norfloxacin

Mexiletine
Norfloxacin may increase the amount of mexiletine in your body, potentially increasing your risk for side effects. Your healthcare provider may choose to monitor you more closely if you take these medications together.
 
Mirtazapine
Norfloxacin may increase the amount of mirtazapine in your body, potentially increasing your risk for side effects. Your healthcare provider may choose to monitor you more closely if you take these medications together.
 
Mycophenolate
Norfloxacin may decrease the amount of mycophenolate in your blood, potentially decreasing its effectiveness. If you take these medications together, your healthcare provider may need to monitor you more closely to make sure mycophenolate is working for you.
 
Nitrofurantoin
Nitrofurantoin can make norfloxacin less effective. In general, it is not recommended to take these medications together.
 
NSAIDs
Taking an NSAID with norfloxacin may increase the risk for central nervous system stimulation, including possible seizures. Talk to your healthcare provider before taking norfloxacin with an NSAID.
 
Probenecid
Taking probenecid with norfloxacin may increase the levels of norfloxacin in your bloodstream, increasing your risk for side effects. Be especially watchful for side effects of norfloxacin if you take these medications together.
 
Propranolol
Norfloxacin may increase the amount of propranolol in your body, increasing your risk for side effects. Your healthcare provider may choose to monitor you more closely if you take these medications together.
 
Quinapril
Quinapril can bind to norfloxacin in the digestive tract, preventing it from being fully absorbed into the bloodstream. Separate your norfloxacin and quinapril doses by at least two hours to help minimize the chance of this interaction.
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Norfloxacin Drug Information

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