Drug Interactions

Norfloxacin may react with a number of other medications (see Drug Interactions With Norfloxacin).

What If I Overdose on This Medication?

As with most medications, it is possible to take too much norfloxacin. If you or someone else may have overdosed on this drug, seek immediate medical attention.
(Click Noroxin Overdose for more information.)

What Should I Do If I Forget a Dose?

If you forget to take your norfloxacin dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the one you missed and continue with your regular schedule. Do not take a double dose. Try to take your norfloxacin on schedule, as missing doses increases the chance of developing antibiotic-resistant bacteria.

How Does Norfloxacin Work?

Norfloxacin works by killing the bacteria that cause the infections. Specifically, norfloxacin interferes with two bacterial enzymes called topoisomerase IV and DNA gyrase. These enzymes are necessary for the bacteria to copy and repair DNA, which are critical steps needed for the bacteria to multiply.

When and How to Take This Medication

Some general considerations to keep in mind during treatment with norfloxacin include the following:
  • Norfloxacin comes in tablet form. It is usually taken every 12 hours, although for gonorrhea, it is usually just given as a single, one-time dose.
  • This medication should be taken on an empty stomach at least one hour before or two hours after a meal.
  • Norfloxacin should not be taken with milk or calcium-fortified juices, such as orange juice. Take it with a glass of water.
  • Make sure you drink plenty of fluids to stay well hydrated during treatment.
  • Norfloxacin is an antibiotic used to treat bacterial infections. It will not treat infections caused by viruses, such as the common cold or flu.
  • You should start to feel better within a couple of days of treatment. However, this does not mean your infection is gone. Make sure you finish the entire course of this medicine. Stopping it too early may cause your symptoms to return or lead to antibiotic resistance.
  • For the medication to work properly, it must be taken as prescribed.
The Dirty, Messy Part of BPH

Norfloxacin Drug Information

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