Precautions and Warnings With Ofloxacin

Antibiotics like ofloxacin are known to cause mild, short-term diarrhea. However, severe, watery, or bloody diarrhea is a cause for concern. Precautions and warnings with ofloxacin also apply to women who are pregnant or breastfeeding, people with severe kidney or liver disease, and people with a history of nerve problems. Thus, it is important to discuss your medical history with your healthcare provider before beginning treatment.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking
 ofloxacin if you have:
 
  • Kidney disease, such as kidney failure (renal failure)
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Tendon or joint problems
  • Nerve problems, such as neuropathy
  • A history of seizures or epilepsy
  • An irregular heartbeat or a heart rhythm problem known as QT prolongation, or have family members with these problems
  • Cerebral arteriosclerosis (hardening and thickening of the arteries of the brain)
  • Any allergies, including to medications, foods, dyes, or preservatives
  • Myasthenia gravis.
     
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
     
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
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