Rifampin Dosage

Available in the form of a capsule or an injection, rifampin is an antibiotic that is typically used once or twice a day. The rifampin dosage your healthcare provider uses will depend on your weight and the reason you are using it, among other factors. Your healthcare provider will determine how long you should receive treatment based on how you respond to the drug.


An Introduction to Your Dosage of Rifampin

The dose of rifampin (Rifadin®) your healthcare provider recommends will vary, depending on several factors, including:
  • Your weight
  • The reason you are using it
  • How you respond to it.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

Recommended Rifampin Dosing Guidelines for Treating Tuberculosis?

The usual recommended dose of rifampin for treating tuberculosis in adults is 10 mg per kg of body weight (about 4.54 mg per lb) daily. For children, the usual recommended dosage is 10 to 20 mg per kg (about 4.54 to 9.09 mg per lb) daily. The maximum recommended dose in adults and children is rifampin 600 mg a day.
When rifampin is taken by mouth in capsule form, it is usually taken once a day. Rifampin injection is given once a day, over a period of 30 minutes to 3 hours.
Rifampin is usually given in combination with other tuberculosis medications. Most people are treated for at least six months. Your healthcare provider will determine how long you need treatment. Longer treatment may be necessary if Mycobacterium tuberculosis (the bacterium that causes tuberculosis) is still detected in the body after six months, if the bacteria are resistant to tuberculosis medications, or in people with a human immunodeficiency virus (HIV) infection.

What Is the Recommended Rifampin Dose for Meningococcal Carriers?

The usual recommended dose of rifampin for people who have meningococcal bacteria in their nose and throat without symptoms (known as meningococcal carriers) is as follows:
  • For adults, the usual dosage is 600 mg twice a day for 2 days
  • For children 1 month of age and older, the usual dosage is 10 mg per kg body weight (about 4.54 mg per lb) twice a day, to a maximum of 600 mg per dose
  • For children under 1 month of age, the usual dosage is 5 mg per kg body weight (about 2.27 mg per lb) twice a day. 

Rifampin Antibiotic Information

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