You should talk with your healthcare provider prior to taking this medication if you have:
- HIV or AIDS
- Kidney disease, such as kidney failure (renal failure)
- Liver disease, such as liver failure, cirrhosis, or hepatitis
- Glucose-6-phosphate dehydrogenase deficiency
- A folic acid deficiency
- Phenylketonuria (PKU)
- A thyroid disorder
- Any other allergies, including allergies to food, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Bactrim and Pregnancy, Septra and Pregnancy, or Sulfatrim and Pregnancy)
- Breastfeeding (see Bactrim and Breastfeeding, Septra and Breastfeeding, or Sulfatrim and Breastfeeding).
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Sulfamethoxazole/Trimethoprim to learn more, including information on who should not take the drug.)