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Vibrio Cholerae

Vibrio cholerae bacteria are typically responsible for the diarrheal illness called cholera. The two types of Vibrio cholerae are Vibrio cholerae Serogroup O1 and Vibrio cholerae Serogroup non-O1. A person can get cholera by drinking water or eating food contaminated with Vibrio cholerae.

 

An Introduction to Vibrio Cholerae

Vibrio cholerae is a type of bacteria that cause cholera (an acute, diarrheal illness that can result in severe dehydration and even death within a matter of hours).
 
Vibrio cholerae are gram-negative rods (see Pictures of Cholera) that are facultatively anaerobic, which means they can survive either with or without oxygen.
 

Types of Vibrio Cholerae

There are two general types of Vibrio cholerae:
 
  • Vibrio cholerae Serogroup O1
  • Vibrio cholerae Serogroup non-O1.
     
Vibrio cholerae Serogroup O1 is the type of Vibrio cholerae that is most often the cause of cholera. Vibrio cholerae Serogroup O139, a Vibrio cholerae Serogroup non-O1 bacterium, is the other cause of cholera. There are about 70 other species of Vibrio cholerae Serogroup non-O1; these other species rarely cause diarrhea.
 

How Common Is Vibrio Cholerae?

Vibrio cholerae is native to the Ganges delta, which is in India and extends into Bangladesh. Since 1817, there have been seven worldwide Vibrio cholerae pandemics. There is an ongoing global pandemic in Asia, Africa, and Latin America that has lasted over four decades. Since 1995, over 80 percent of reported cases of Vibrio cholerae infections have occurred in Africa.
 
Vibrio cholerae infections have been very rare in industrialized nations for the last 100 years. In the United States, there are zero to five cases per year.
 
In 2003, 111,575 cases from 45 countries were reported to the World Health Organization.
 

Transmission of Vibrio Cholerae

A person may get cholera by drinking water or eating food contaminated with Vibrio cholerae. In an epidemic, the source of Vibrio cholerae contamination is usually the feces of an infected person. Cholera can spread rapidly in areas with inadequate treatment of sewage and drinking water.
 
Vibrio cholerae may also live in the environment in brackish (saltwater) rivers and coastal waters. Shellfish, when eaten raw, have been a source of Vibrio cholerae, and a few people in the United States have contracted cholera after eating raw or undercooked shellfish from the Gulf of Mexico.
 
Vibrio cholerae is not likely to spread directly from one person to another; therefore, casual contact with an infected person is not a risk for becoming ill.
 
Once Vibrio cholerae is ingested, the bacteria travel to the small intestine where they begin to multiply. Vibrio cholerae then begins producing its toxin, which is the main cause of watery diarrhea, a characteristic symptom of cholera.
 
A person needs to ingest a lot of Vibrio cholerae in order to develop symptoms of cholera. The amount needed is decreased in those taking antacids, or following a meal, when the acids in the stomach are neutralized.
 
Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: Arthur Schoenstadt, MD